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Add GISAID
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ljl-covid committed Dec 20, 2020
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Expand Up @@ -237,6 +237,7 @@ Note that the WHO will generally be unable to make statements that their more pr
* [Nextstrain genomic epidemiology](https://nextstrain.org/ncov) showing genetic variants of the virus by area and other factors (see also [this article about "cryptic" transmission](https://bedford.io/blog/ncov-cryptic-transmission/))
* [COVIDCG](https://covidcg.org/) is a genetics browser was designed to empower diverse projects on SARS-CoV-2 transmission, evolution, emergence, immune interactions, diagnostics, therapeutics, vaccines, and tracking of interventions.
* [SARS-CoV-2 Mutations of Interest](https://github.com/emmahodcroft/cluster_scripts) is a repository maintained by [Emma Hodcroft](https://twitter.com/firefoxx66) containing brief information and highlights about mutations that may have significance, together with dedicated Nextstrain builds for each of them
* [Official hCoV-19 Reference Sequence](https://www.gisaid.org/epiflu-applications/hcov-19-reference-sequence/) and [Genomic epidemiology of hCoV-19](https://www.gisaid.org/epiflu-applications/phylodynamics/) at [GISAID](https://www.gisaid.org/), which offers many other COVID-19 resources
* [How the novel coronavirus has evolved](https://graphics.reuters.com/HEALTH-CORONAVIRUS/EVOLUTION/yxmpjqkdzvr/), a Reuters article breaking down the evolution and mutations of the virus and the way they affected different areas of the world in a way more understandable to the layman than Nextstrain
* [Structural genomics and interactomics of SARS-CoV-2 novel coronavirus](http://korkinlab.org/wuhan) by Korkin Lab at the Worcester Polytechnic Institute
* [Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2](https://www.biorxiv.org/content/10.1101/2020.04.29.069054v1), an April 30 preprint highlighting how a mutated form of the virus appears to be circulating much faster and taking over the original strain in Europe and elsewhere, with another preprint finding that [Global Spread of SARS-CoV-2 Subtype with Spike Protein Mutation D614G is Shaped by Human Genomic Variations that Regulate Expression of TMPRSS2 and MX1 Genes](https://www.biorxiv.org/content/10.1101/2020.05.04.075911v1) although an [article on ArsTechnica](https://arstechnica.com/science/2020/05/draft-study-conclusions-on-sars-cov-2-mutation-overstep-data-grab-headlines/) highlights various issues other researchers have raised with this paper; later research shows [SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo](https://science.sciencemag.org/content/early/2020/11/11/science.abe8499), and [Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus](https://www.cell.com/cell/fulltext/S0092-8674(20)30820-5), an analysis published on Cell, wraps up the situation as it's known as of November 2020
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